 miRNA description for miR-421 |
| miRNA accession |
miR-421 |
| Species |
Homo sapiens |
| miR-421 identified in exosomes derived from the following tissue/cell type |
|
Colorectal cancer cells
|
25330373
|
|
Endothelial cells
|
26027894
|
|
Plasma
|
23663360
|
|
Serum
|
18589210
|
| Experiment description of studies that identified miR-421 in exosomes |
| 1 |
| Experiment ID |
223 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
25330373
|
| Organism |
Homo sapiens |
| Experiment description |
Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA-enrichment signatures |
| Authors |
Ji H, Chen M, Greening DW, He W, Rai A, Zhang W, Simpson RJ |
| Journal name |
PLoS One
|
| Publication year |
2014 |
| Sample |
Colorectal cancer cells |
| Sample name |
LIM1863 |
| Molecules identified in the study |
miRNA
Protein |
| Methods used in the study |
RT-PCR
Western blotting |
|
|
| 2 |
| Experiment ID |
226 |
| Identified molecule |
miRNA
|
| Identification method |
| Small RNA sequencing (Illumina HiSeq 2000 (Solexa) |
|
|
| PubMed ID |
26027894
|
| Organism |
Homo sapiens |
| Experiment description |
Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting |
| Authors |
Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar |
| Journal name |
Journal of Extracellular Vesicles
|
| Publication year |
2015 |
| Sample |
Endothelial cells |
| Sample name |
HMEC-1 |
| Molecules identified in the study |
miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA |
| Methods used in the study |
Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting |
|
|
| 3 |
| Experiment ID |
222 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
23663360
|
| Organism |
Homo sapiens |
| Experiment description |
Characterization of human plasma-derived exosomal RNAs by deep sequencing |
| Authors |
Huang X, Yuan T, Tschannen M, Sun Z, Jacob H, Du M, Liang M, Dittmar RL, Liu Y, Liang M, Kohli M, Thibodeau SN, Boardman L, Wang L |
| Journal name |
BMC Genomics
|
| Publication year |
2013 |
| Sample |
Plasma |
| Sample name |
Plasma - Normal |
| Molecules identified in the study |
miRNA
tRNA
snRNA
snoRNA
rRNA
piRNA
lncRNA |
| Methods used in the study |
RT-PCR |
|
|
| 4 |
| Experiment ID |
45 |
| Identified molecule |
miRNA
|
| Identification method |
|
| PubMed ID |
18589210
|
| Organism |
Homo sapiens |
| Experiment description |
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. |
| Authors |
Taylor DD, Gercel-Taylor C |
| Journal name |
GO
|
| Publication year |
2008 |
| Sample |
Serum |
| Sample name |
Serum - Papillary adenocarcinoma of ovary |
| Molecules identified in the study |
Protein
miRNA |
| Methods used in the study |
Western blotting
467microRNA Array |
|
|